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Michael Lever Selected Research

Betaine (C.B.B.)

5/2015Variation of betaine, N,N-dimethylglycine, choline, glycerophosphorylcholine, taurine and trimethylamine-N-oxide in the plasma and urine of overweight people with type 2 diabetes over a two-year period.
10/2014Extreme urinary betaine losses in type 2 diabetes combined with bezafibrate treatment are associated with losses of dimethylglycine and choline but not with increased losses of other osmolytes.
7/2014Fenofibrate causes elevation of betaine excretion but not excretion of other osmolytes by healthy adults.
1/2014Betaine and Trimethylamine-N-Oxide as Predictors of Cardiovascular Outcomes Show Different Patterns in Diabetes Mellitus: An Observational Study.
9/2012Betaine homocysteine methyltransferase is active in the mouse blastocyst and promotes inner cell mass development.
7/2012Variability of plasma and urine betaine in diabetes mellitus and its relationship to methionine load test responses: an observational study.
1/2012Plasma betaine concentrations correlate with plasma cortisol but not with C-reactive protein in an elderly population.
1/2012Betaine and secondary events in an acute coronary syndrome cohort.
1/2011Plasma lipids and betaine are related in an acute coronary syndrome cohort.
10/2010Fibrates plus betaine: a winning combination?
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Michael Lever Research Topics

Disease

6Heart Failure
01/2014 - 05/2008
4Metabolic Syndrome (Dysmetabolic Syndrome X)
07/2014 - 10/2009
4Diabetes Mellitus
01/2014 - 10/2009
4Vascular Diseases (Vascular Disease)
03/2008 - 03/2002
4Chronic Kidney Failure (Chronic Renal Failure)
04/2007 - 03/2002
3Acute Coronary Syndrome
01/2014 - 01/2011
2Type 2 Diabetes Mellitus (MODY)
05/2015 - 10/2014
2Myocardial Infarction
01/2014 - 10/2008
2Inflammation (Inflammations)
01/2012 - 07/2008
2Cardiovascular Diseases (Cardiovascular Disease)
10/2010 - 01/2005
2Hypertension (High Blood Pressure)
10/2009 - 05/2008
2Hyperhomocysteinemia
01/2005 - 03/2002
1Overweight
05/2015
1Coronary Disease (Coronary Heart Disease)
01/2014
1Unstable Angina
01/2014
1Fetal Resorption
09/2012
1Body Weight (Weight, Body)
07/2012
1Hip Fractures (Intertrochanteric Fractures)
01/2012
1Wounds and Injuries (Trauma)
01/2012
1Trimethylaminuria
02/2011
1Confusion (Bewilderment)
06/2010
1Parkinson Disease (Parkinson's Disease)
05/2008
1Neoplasms (Cancer)
05/2008
1Renal Insufficiency (Renal Failure)
04/2007
1Acute Kidney Injury (Acute Renal Failure)
04/2007
1Homocystinuria
05/2004

Drug/Important Bio-Agent (IBA)

18Betaine (C.B.B.)FDA Link
05/2015 - 03/2002
6HomocysteineIBA
07/2012 - 05/2004
5dimethylglycineIBA
05/2015 - 11/2004
4trimethyloxamine (trimethylamine N-oxide)IBA
05/2015 - 06/2010
3Choline (Choline Chloride)IBA
05/2015 - 03/2008
3LipidsIBA
01/2011 - 01/2005
3coenzyme Q10 (CoQ10)IBA
10/2009 - 05/2008
2BezafibrateIBA
10/2014 - 10/2009
2Fibric Acids (Fibrates)IBA
10/2014 - 10/2010
2Methionine (L-Methionine)FDA Link
07/2012 - 03/2002
2Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
10/2010 - 01/2009
1Glycerylphosphorylcholine (Choline Alfoscerate)IBA
05/2015
1CarbonIBA
05/2015
1TaurineFDA Link
05/2015
1Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric
01/2014
1chenodeoxycholate sulfate conjugate (CDCS)IBA
01/2014
1DNA (Deoxyribonucleic Acid)IBA
01/2014
1Hydrocortisone (Cortisol)FDA LinkGeneric
01/2012
1C-Reactive ProteinIBA
01/2012
1Carnitine (L-Carnitine)FDA LinkGeneric
01/2012
1EnzymesIBA
02/2011
1trimethylamineIBA
02/2011
1Pharmaceutical PreparationsIBA
01/2011
1Complement System Proteins (Complement)IBA
10/2010
1Protons (Proton)IBA
06/2010
1Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
01/2009
1Peptides (Polypeptides)IBA
10/2008
1UbiquinoneIBA
10/2008
1CholesterolIBA
10/2008
1Brain Natriuretic Peptide (Natrecor)FDA Link
10/2008
1antineoplaston A10 (A 10)IBA
04/2007
1Betaine-Homocysteine S-Methyltransferase (Betaine Homocysteine Methyltransferase)IBA
05/2004
1Pyridoxine (Pyridoxin)FDA LinkGeneric
03/2002
1Folic Acid (Vitamin M)FDA LinkGeneric
03/2002

Therapy/Procedure

3Therapeutics
10/2010 - 05/2008
1Continuous Ambulatory Peritoneal Dialysis (CAPD)
04/2007